For years physicians have been using MRIs for internal imaging, but now, reseachers may have developed a way to use the same MRI technique to treat brain cancer by delivering the drug directly to the target.Surgeons at the University of California, San Diego School of Medicine and Moores Cancer Center used MRI navigational technology from MRI Interventions to inject the investigational gene therapy Toca 511, or vocimagene amiretrorepvec, into a brain tumor to make it more susceptible to chemotherapy. Tocagen's Toca 511 is a retrovirus that replicates in cancer cells such as glioblastoma, according to a UCSD release. And MRI Interventions' ClearPoint technology helps target it directly into those tumors.
Researchers are hoping this direct injection will also help decrease the number of cells exposed to the drug during the treatment. What other types of disease could this technique help treat? How will this development impact other drug delivery technologies for cancer treatment?
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