Jelly-based delivery system could be used to treat diabetes

A new jelly-based drug could assist in delivering diabetes medication. The jelly-based delivery system was developed at Duke University and could deliver the drug in a more effective and efficient way. Peptide drugs are broken down immediately by our bodies, this new jelly-based system will allow drug to gradually be released over time.

 Copies of the peptide drug are fused with heat-sensitive polymers. The heat sensitivity means that the fusion protein turns to jelly once inside the body and is gradually broken down by enzymes to release the drug over time.The treatment functions in a similar way to microsphere-release technology, which sees polymer microspheres loaded up with peptide drugs and then injected under the skin.

The jelly is painless, less expensive, and easier to inject. It is said that the jelly-based system could also decrease the number of injections a patient gets while making the medication last longer. Longer lasting medication would raise patient compliance, minimize doctors visits, and make the overall treatment a better experience for the patient. This drug could especially benefit patients because of the long lasting effects, so how does a drug that is used less more profitable?

When you’re designing the formulation for the delivery system, how can predict how it will behave? At the 17th Annual Drug Delivery Partnerships, Keith Horspool, Vice President, Pharmaceutics, BOEHRINGER INGELHEIM, leads our session - Fixed Dose Combinations: Use Predictive Studies to Establish Potential for Success or Failure.

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