Thursday, July 5, 2012

Calcium Carbonate nano particles for drug delivery

Current chemotherapy treatment is effective, but not real targeting abilities and only stop the growth of tumors. Researchers in Potsdam-Golm developed a new method of nanoparticle drug delivery that use porous calcium carbonate microspheres to carry medication to the desired treatment location. The boxes can be filled with medical substances.

According to OMICS Group, this is how they efficiently deliver the medication:

The Potsdam-based researchers then surround the filled CaCO3 spheres with a web consisting of long protein chains — alternatively, they can also use polymer threads for this purpose. The next step involves dissolving the CaCO3 template using an acid. The nanoparticles then arrange themselves into a porous sphere that is encased in the protein web. “We can very easily combine substances to form a multifunctional unit and tailor their chemical and physical properties to the required function,” says M√∂hwald.

The protein web not only covers the hollow sphere, it also makes it biocompatible and can contain biochemical signalling substances that send the spheres directly to their target in the body.


Want to learn more about Drug Delivery? The Drug Delivery Partnerships conference will take place February 6-8, 2013 in San Diego, Ca. For information on how to become involved in the program, email Conference Director Heather King.  For a recap on the 2012 Executive Summary, download it here.

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